Abstract
Various techniques have been attempted in the past to truly regenerate the lost bone structures. Owing to its stimulatory effect on angiogenesis and epithelialization, concentrated growth factor (CGF) is an excellent material for enhancing bone healing. The purpose of these case series is to document the beneficial role of CGF in the healing of different bone defect areas. This report describes four female patients presented with (lateral cyst on tooth 22; periimplantitis on mandibular left first premolar area; furcation lesion on tooth 36, periapical abcess on teeth 11-21). Mucoperiosteal full-thickness flaps were elevated to perform the surgical debridement of lesion areas in all patients. Then, minced CGF mixed with bone graft was applied to fill the defects. Recall radiographs of cases showed satisfactory healing of the bony defects. According to the results obtained in these case reports, the positive clinical impact of additional application of CGF with bone graft materials in treatment of bone defects is based on significant radiographic defect bone fill.
Highlights
The bony defects can be developed by periodontal disease, tooth loss, trauma and infection
Bony defects in the jaws occur for various reasons such as infections, periodontal diseases, tumors, or cysts
Growth factors are bioactive proteins which control the process of wound healing [6]. These growth factors are present in blood, within platelets and in plasma and platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and recently concentrated growth factor (CGF) have been used for reconstruction of bony defects and increasing the success rate of bone grafting therapy [7,8]
Summary
Gökmenoğlu et al Int J Oral Dent Health 2016, 2:029 Volume 2 | Issue 2 ISSN: 2469-5734.
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