Treatment of Circulatory Collapse of Experimental Venous Occlusion: Use of Adrenal Cortical Extract and Saline Solution

Abstract

SummaryThe shocklike syndrome of circulatory collapse and prostration was induced in a series of 18 dogs by a regional venous occlusion. Treatment at the time of collapse, by infusion of ACE and physiological saline, resulted in a marked increase in survival time in 6. In a control group of 12, saline infusion alone prolonged survival time in 2. ACE alone in a series of 12 proved ineffective.