Abstract
The objective: to evaluate the possibility of the long-term monotherapy with the Gentos Forte® in men with chronic prostatitis (CP) and diabetes mellitus (DM) with lower urinary tract symptoms (LTS).Patients and methods. The advisory polyclinic SI «Institute of Urology of NAMS of Ukraine» was observed 78 men. The first group (n=42) consisted of persons with CP + signs on the background of LUTS verified diabetes type II (mean age 49,2±1,9 years) who received monotherapy Gentos Forte® (Bittner Pharma). A control group (group II) were patients with the same condition (mean age 45,2±1,0 years) treated with monotherapy with vitamin E 400 mg/once daily (n=31). History duration on diabetes disease averaged 5,6±0,7 years; Chronic prostatitis – an average of 13,5±0,7 years; for the duration of symptoms of LUTS – on average 2,0±0,4 years. The comparison group (Group III) were 5 healthy volunteers of age who are not receiving any treatment.Results. As a result of treatment it was found that monotherapy with Gentos Forte® in patients of the I group is effective. The results of the study indicate that monotherapy with Gentos Forte® is a reliable alternative in individuals with a clinical Association CP, the DM and LUTS, and the effectiveness of the therapy directly depends on the process and duration of therapy.Conclusions. 1. The clinical course of chronic prostatitis on a background of diabetes, is characterized by a persistent lower urinary tract symptoms, which requires long-term therapy, taking into account all the links of the pathogenesis of chronic inflammatory diseases.2. Monotherapy Gentos Forte®, in terms of 120 days has helped to improve the patient’s condition, with decreasing LUTS manifestations 27.2%, improving the quality of life index of 37.2%, a decrease in prostate size by an average of 15.3%.3. Monotherapy Gentos Forte® is highly effective and safe, improves the quality of life of men through the elimination of lower urinary tract symptoms, with the improvement of erectile function in 69.0% of patients in term of 120 days.4. For 120 days use of the Gentos Forte®, 92.8% of men were satisfied with the results of treatment and want to continue it further.
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