Abstract
Introduction: Chalazion is a common eyelid margin disorder manifesting as granulomatous inflammation associated with meibomian gland lipids. There are three methods of treating chalazian: IntralesionalTriamcinolone Acetonide (0.1-0.3 ml of 40mg/ml), Incision and Curettage and Conservative Treatment (hot compression +lid hygiene + antibiotic ointment).Methods: Patients with chalazian presenting to the Outpatient Department (OPD) of the Lumbini Eye Institute and Research Center (LEIRC) from 15 March 2017 to 15 July 2017 were included in the study. They underwentany of the three procedures (Conservative Treatment or Triamcinolone Acetonide Injection or Incision and Curettage) according to their choice. We compared all three methods of treatment of chalazion on follow upvisit at 2 weeks, which was done to determine effectiveness in terms of reduction of size or complete resolution of the chalazia.Results: Out of 112 patients enrolled in study 65(58%) were females and 47(42%) were male with a male: female ratio of (0.7:1). The mean age of involvement was 25.7years (SD 10.3). At 2 weeks follow up there wascomplete resolution in incision and curettage (I and C) group 77 % (41/53) and in Triamcinolone Acetonide (TA) injection group 63 %( 20/32). Pearson’s correlations showed that I and C were superior to any other forms of intervention for any size of chalazian followed by intralesional injection of TA.Conclusion: Incision and Curettage remained the best choice for the treatment of chalazion followed by triamcinolone acetonide injection but may need multiple injections.
Highlights
Chalazion is a common eyelid disease caused by plugged meibomian glands and chronic lipogranulomatous inflammation
Incision and Curettage remained the best choice for treatment of chalazionfollowed by triamcinolone acetonide injection but may need multiple injections
Male to Female ratio was 0.7:1.Left upper lid was involved in 41(36.6%), followed by the right upper lid in 36(32.1%), right lower lid in 20(17.9%), left lower lid was involved in 15(13.4%).The mean age of the patients was 25.7years (SD 10.3).Patients age was divided into 5 categories out of which most presented in age group of 17-30 = 76(67.9%), while 14(12.5%) patients were in the age group of
Summary
Chalazion is a common eyelid disease caused by plugged meibomian glands and chronic lipogranulomatous inflammation. It can affect any ages and may cause local eye symptoms such as irritation, inflammation and cosmetic disfigurement.[1] Histopathological examination of chalazion reveals the presence of many neutrophils, lymphocytes, plasma cells and foreign body giant cells situated around cavities and clefts, which are assumed to be filled with lipid material derived from the meibomian gland.[2] Different treatment options for chalazion include conservative management such as hot compresses and topical antibiotics, incision and curettage and intralesional steroid injection[3]. This study was done to compare all three methods of treatment of chalazion and find out the most effective method for treatment
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