Treatment of cavernous hemangioma of the tongue by continuous intra-arterial infusion of 5-fluorouracil

Abstract

A thirty-seven year old white woman with an enlarging cavernous hemangioma of the tongue, which recurred after sclerosing therapy and surgery had been given, was treated with continuous intra-arterial infusion chemotherapy using the antimetabolite, 5-fluorouracil. The salutary results, consisting of reduction in size and vascularity of the lesion, have lasted a year and five months to the time of publication of this report, and suggest that this means of therapy may be useful in the management of certain enlarging and troublesome vascular malformations.