Abstract
Café-au-lait macules are a benign cutaneous pigmentary disorder with variable responses to laser treatment. We treated a 21-year-old female with recurred café-au-lait macules on the thigh using a combination of frequency-doubled Q-switched neodymium-doped yttrium aluminum garnet laser followed by 10 sessions of fractional laser, via a novel 1,927 nm fractional thulium laser. At the 11-month follow-up after the last treatment, no foci of re-pigmentation were found. We suggest that fractional thulium laser resurfacing, combined with conventional Q-switched laser treatment, can be used as a safe and effective adjuvant therapy in patients with treatment-resistant café-au-lait macules.
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