Treatment of Bovine Papilloma

Mohammed A Hamad

doi:10.30539/iraqijvm.v36i0e.377

Mohammed A Hamad

Open Access

https://doi.org/10.30539/iraqijvm.v36i0e.377

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Abstract

In this study (35) cows suffering from bovine papilloma were subjected for three differenttypes of treatments; The First group involved 15 animals treated with autogenous vaccine.The Second group involved 10 animals treated with prepared cell culture vaccine .While thethird group involved 10 cows treated with virulent local Newcastle disease virus. In the Firsttwo groups the warts were surgically removed from cows showing lump lesions on skin ofabdomen, neck and udder, and transferred aseptically to laboratory by using transport media.Treatment of cows in the first group involved preparation of autogenous formalin (0.5%)in activated vaccine. Vaccination of these animals result in regression of the warts startedafter 2 or 3 weeks and complete disappearance of the warts after 30-60 days with a meanduration of 44.9 days.Treatment of the second group involved preparation of papilloma cell culture inactivatedvaccine 0.5% formalin from 3 papilloma cases. The response of these vaccinated cows resultin regression of the warts lesions started after 2 or 3 weeks post the first vaccinal dose andcomplete disappearance of the warts after 30-60 days, with mean 43.8 days.Treatment of the third group involved using of virulent NDV by subcutaneous injectionand infiltration around the warts. Results showed successful regression of warts within ashorter period with mean of 30.1 days compared to treatment with autogenous and cell culturevaccine, with complete regression of the warts within 15-28 days.

Highlights

SummaryIn this study [35] cows suffering from bovine papilloma were subjected for three different types of treatments; The First group involved 15 animals treated with autogenous vaccine
Bovine papillomatosis is a common viral disease of the skin, mostly of young cattle, manifested as benign tumours or warts, caused by bovine papillomavirus (BPV) [1]. (BPV)associated diseases are important in veterinary medicine and can be considered as possible important models for the study of human papillomavirus (HPV).Six types of BPV have been described [2], and recently, four other types were reported
BPV-1 causes teat and penile fibropapillomas; BPV-2 is associated with cutaneous warts, alimentary fibropapillomas and urinary bladder tumors; BPV-3 causes cutaneous papillomas; BPV-4 is associated with pure epithelial papillomas of the upper gastrointestinal tract; BPV-5 induces fibropapillomas of the udder; BPV-6 causes papillomas of the teats; BPV-8 causes cutaneous papillomas; BPV-9/10 are associated with epithelial squamous papillomas of the udder [3]

Summary

In this study [35] cows suffering from bovine papilloma were subjected for three different types of treatments; The First group involved 15 animals treated with autogenous vaccine. Treatment of cows in the first group involved preparation of autogenous formalin (0.5%) in activated vaccine Vaccination of these animals result in regression of the warts started after 2 or 3 weeks and complete disappearance of the warts after 30-60 days with a mean duration of 44.9 days. Treatment of the second group involved preparation of papilloma cell culture inactivated vaccine 0.5% formalin from 3 papilloma cases. The response of these vaccinated cows result in regression of the warts lesions started after 2 or 3 weeks post the first vaccinal dose and complete disappearance of the warts after 30-60 days, with mean 43.8 days. ‫) بقزة ٌعاوىن مه الأورام الحلٍمٍت عىلضج بزلارت أووىا مخخلفوت موه العلاصواثا المضمىعوت‬35( ‫اصزٌج الذراست على‬ ‫( حٍىاوواث عىلضوج باللقواط المحموز موه‬10( ‫ والمضمىعت الزاوٍوت شوملج‬.ً‫) حٍىان عىلضج باللقاط الذاح‬15( ‫الأولى شملج‬ ً‫ وو‬. ‫) حٍىاو واث عىلضووج ب والعخزة المحلٍ وت الرووارٌت لف واٌزوص الىٍىكاسوو‬10( ‫الووشر الخل وىي والمضمىع وت الزالز وت ش وملج‬ ‫المضمىعت الأولى مه الأبقار الخً حعاوً مه آ اث ورمٍت على شك كخ ً مىطقت الوبطه والزقبوت والروز اسٌلوج صزاحٍوا‬ ‫ علاس الأبقار ً المضمىعت الأولى بىاسوطت اللقواط الوذاحً المقخوىم المحروز‬.‫ووقلج بىاسطت وسط سرعً واق إلى المخخبز‬ ‫ أسابٍع موه بذاٌوت العولاس ولوىحع إخخفوا‬2-3 ‫مه حلك اَ ت الىرمٍت ولاسخضابت العلاصٍت ً حلك الحٍىاواث الملقحت بذأث مه‬ ‫شوم عولاس المضمىعوت الزاوٍوت ححروٍز‬.‫ ٌىم‬45 ‫) ٌىم مه بوذ العولاس وبمعوذم خوزة اسوخضابت‬30-60( ‫اَ ت الىرمٍت كلٍا مه‬ ‫ ىرمالٍه مه رلارت حالاث عاوج مه الأورام الحلٍمٍت البقزٌت حٍذ اسوخضابج الأبقوار‬%5 ‫لقاط الشر الخلىي المقخىم بىسبت‬ ‫ ٌوىم بمعوذم‬30-60 ‫الملقحت بذئا مه الأسبى الأوم والزاوً مه إعطا أوم صزعت علاصٍوت وكوان الاخخفوا الكلوً للوىرم موه‬ ‫ عىلضوج المضمىعوت الزالزوت باسوخخذام العخوزة المحلٍوت الروارٌت لفواٌزوص الىٍىكاسو بىاسوطت الحقوه‬.43.8 ‫اسخضابت علاصٍوت‬ ً‫ مقارووت موع اللقواط الوذاح‬30.1 ‫ أظهزث الىخائش اخخفا حام للىرم وبفخزة قصٍزة وبمعوذم‬.‫ححج الضلذ والارحشاط داخ الىرم‬

Introduction

Materials and Methods

Findings

Results

Discussion