Treatment of Basilar Artery Occlusion using Various Techniques of Interventional Radiology

Abstract

Basilar Artery Occlusion (BAO) is a rare cause of stroke, occurring in about 1% of all the cases. BAO is characterized by bad prognosis and high death rate, which is about 75-91%. Neurological symptoms which accompany BAO are of large variety. BAO may occur suddenly, with or without previous prodromal symptoms or it may proceed progressively. Basilar artery occlusion always demands quick diagnosis and treatment. We are describing 5 cases of patients with basilar artery occlusion who were subjected to endovascular methods. The patients were treated with different intravascular techniques. Two patients had a stent Solitaire FR inserted, two others were applied targeted thrombolysis, one patient had combined therapy using targeted thrombolysis and mechanical thrombectomy- Penumbra device. Neurological symptoms were determined by using National Institutes of Health Stroke Scale (NIHSS). 60% of patients achieved the result, according to NIHSS, equal 0 or 1 point or improvement of ≥ 10 points, which is defined as neurological state changing for the better as well as the reduction of symptoms. Unblocking the basilar artery (TICI ≥ 2b) was successful with 80% of patients. The lack of disability was stated with 40% of the group under treatment (mRS ≤ 2). No patient had any complications connected with intravascular treatment. The treatment of basilar artery occlusion is difficult as nowadays there are no precise guidelines defining the most successful therapy. Our study shows that using intravascular methods is a good alternative for standard therapy of basilar artery occlusion, especially with those patients who cannot be qualified for intravenous thrombolysis due to overrunning the time window or with whom intravenous using of rt-PA was not efficient. The usage of endovascular methods is hoped to have great future prospects.