TREATMENT OF BASAL CELL EPITHELIOMA BY INJECTION OF TISSUE EXTRACTS

Abstract

IN A PREVIOUS report 1 the results of treatment of basal cell epitheliomas with tissue extracts prepared from human spleen and liver were described. The small number of normal human organs available for this work limited the number of patients who could be accepted for treatment. Obviously, the immediate problem resolved itself into the location of more plentiful sources of the effective principle. In the laboratory constant emphasis has been placed on the problem of determining the nature of the principle. It is hoped that a more thorough understanding of its nature will be helpful in eventually pointing the way toward synthesis, as has been the case with some of the vitamins. Our more immediate approach, however, has been of the cut and try type, a testing of extracts of organs which were readily available. Fardon, Brotzge and Loeffler, 2 for example, in working with heterologous tissue extracts, demonstrated that