Abstract

Investigators at Massachusetts General Hospital, Boston, MA, performed a multicenter, 9-week, double-blind, placebo-controlled, dose-optimization study of guanfacine extended release (GXR, <4 mg/d) adjunctive to a long-acting psychostimulant for ADHD continued in 461 subjects.

Highlights

  • Investigators at Massachusetts General Hospital, Boston, MA, performed a multicenter, 9-week, double-blind, placebo-controlled, dose-optimization study of guanfacine extended release (GXR,

  • GXR treatment groups showed significantly greater improvement from baseline compared with placebo plus psychostimulant

  • Small mean decreases in pulse, systolic, and diastolic blood pressure were observed in GXR treatment groups

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Summary

Introduction

Investigators at Massachusetts General Hospital, Boston, MA, performed a multicenter, 9-week, double-blind, placebo-controlled, dose-optimization study of guanfacine extended release (GXR,

Results
Conclusion
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