Treatment of addictions with special reference to anorexia nervosa

Abstract

Anorexia nervosa (AN) is a disease affecting mainly young women. It involves a pathological desire to be thin and has a complex etiology. Treatments, which have varying degrees of success, focus on medication or supervised counseling, sometimes in a hospital setting. AN has several possible co-morbidities, including obsessive-compulsive disorder, depression, and anxiety. In this article, it is hypothesized that since AN has characteristics in common with those of addiction, it could possibly be treated with supplements, such as N-acetylcysteine (NAC), which act to restore glutamate homeostasis in the nucleus accumbens and have been successfully employed in the treatment of substance abuse and various addictive behaviors.