Treatment of acute pain: comparison of the efficacy of ibuprofen lysinate and ibuprofen

Abstract

Relief that is rapid and effective is wanted when treating pain. A double-blind, placebo-controlled study investigated the efficacy, safety and tolerability of ibuprofen lysinate, ibuprofen acid and placebo in acute pain following the extraction of wisdom teeth. Ibuprofen lysinate and ibuprofen acid were similarly well-tolerated and similarly effective in terms of pain relief over six hours. But against expectations, the onset of action of ibuprofen lysinate was not significantly faster than that of ibuprofen acid.