Abstract
Treatment of Acute Liver Failure in Resource-Constrained Settings without Transplantation Facilities Can Be Improved.
Highlights
Acute liver failure affects previously healthy and often young people and has a very high mortality due to rapid multi-organ failure
Even though liver transplantation is the treatment of choice nowadays, the survival rate without liver transplantation in adults is as high as 40% in high-income countries [5, 6]
We propose a practical approach that can be used in Intensive Care Unit-equipped hospitals in resource-constrained countries to try and reduce the high mortality rate where liver transplantation is not available
Summary
Acute liver failure affects previously healthy and often young people and has a very high mortality due to rapid multi-organ failure. The diagnosis is based on the presence of coagulopathy (International normalized ratio >2 or prothrombin rate
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