Treatment of acne scars using the microneedling and drug delivery technique

Abstract

Acne vulgaris is one of the most common skin diseases and most often results in scars that are typically associated with aesthetic and psychological problems. To date, there is no standardized treatment for this kind of scarring. Objectives: To evaluate the improvement of distensible type acne scars on the face after treatment with the microneedling technique, followed by the topical application of a gel containing growth factors. Methods: Ten patients with acne scars who were treated from 2012 to 2014 and met the inclusion criteria were selected. All underwent 3 microneedling sessions with intervals of 1 to 2 months, with a 1-year follow up. Pre- and post- procedure photographs were carried out with a regular digital camera, and with a digital camera with a 3D system. Skin biopsies were performed prior to treatment, and 30 days after the last session. Results: Eight patients completed the study. Among these, seven showed a random reduction in the roughness of the scars in the analyzed area, seven showed a decrease in melanin with a homogenization of its distribution across the skin, and seven patients showed an increase in hemoglobin in the area being studied. The appearance of the scars varied among the eight patients. Deep ice-pick type scars did not improve with the procedure. Conclusions: The studied treatment promotes overall improvement in skin texture and a discreet effect on acne scars