Treatment of a Rare Ganglioneuroma With Resection and Reconstruction of the Mandible: A Case Report and Literature Review

Abstract

Ganglioneuromas are rare neuroblastic tumors that develop from the neural crests of the sympathetic nervous system. Because ganglioneuromas of the mandible have been infrequent, they do not have a standardized management protocol. As of 2000, only 5 cases had been reported. Ganglioneuromas are unique tumors that can undergo histologic maturation from a malignancy to a benign variant. We present the case of a 15-year-old boy with a ganglioneuroma of the mandible and the results of surgical management, including immediate reconstruction with a free fibula microvascular flap.