Abstract
Acne is a common inflammatory skin disease which affects the pilosebaceous units of the skin. It can have severe psychological effects and can leave the patient with severe skin scarring. There are four well-recognized pathological factors responsible for acne which is also the target for acne therapy. In this review, different treatment options are discussed, including topical (i.e., retinoids, and antibiotics) and systemic (i.e., retinoids, antibiotics, and hormonal) treatments. Since the general public has been showing an increasing interest in more natural and generally safer treatment options, the use of complementary and alternative medicines (CAM) for treating acne was also discussed. The use of physical therapies such as comedone extraction, cryoslush therapy, cryotherapy, electrocauterization, intralesional corticosteroids and optical treatments are also mentioned. Acne has been extensively researched with regards to the disease mechanism as well as treatment options. However, due to the increasing resistance of Propionibacterium acnes towards the available antibiotics, there is a need for new treatment methods. Additionally, the lack of necessary evidence on the efficacy of CAM therapies makes it necessary for researchers to investigate these treatment options further.
Highlights
Acne vulgaris is a common chronic inflammatory disease of the skin
Past research suggests that genetic influence combined with comedogenic hormones produce abnormal volumes of sebum which contribute to acne lesions [1,3,10]
Erythromycin is a macrolide antibiotic that attaches to the 50S ribosomal unit of bacterium and prevents translocation, which is necessary for protein synthesis of the bacteria [8]
Summary
Acne vulgaris is a common chronic inflammatory disease of the skin Acne has many negative effects on young adolescents It causes discomfort, emotional stress, disfigurement and even permanent scarring to the skin. Past research suggests that genetic influence combined with comedogenic hormones (especially androgens) produce abnormal volumes of sebum which contribute to acne lesions [1,3,10]. 21, 1063 genetic 2016, influence combined with comedogenic hormones (especially androgens) produce abnormal volumes of sebum which contribute to acne lesions [1,3,10].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
