Abstract
Severe sepsis and septic shock are common health care problem with high mortality. In 2001, Early goal directed therapy was introduced, early appropriate therapy impact on the outcome. In 2012, the âSurviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012â was updated. Since then, several landmark studies recently demonstrated that modified guidelines. We review the treatment guidelines of severe sepsis and septic shock. Key Words: Severe sepsis; Septic shock; Management of sepsis
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