Treatment for malignant tumors complicated with disseminated herpes zoster

Abstract

Objective To explore the treatment for malignant tumors complicated with disseminated herpes zoster, and then compare with malignant tumors complicated with unilateral herpes zoster.Methods The data on 9 patients with malignant tumors and complicated with disseminated herpes zoster who had been treated from January 2000 to July 2011 were retrospectively analyzed,and so were the data on the 28 patients complicated with unilateral herpes zoster herpes zoster who had been treated during the same time.Results There was a significant difference in the CD4/CD8 rate between the patients with disseminated herpes zoster and those with unilateral herpes zoster ( 44.44％ vs.10.71％ or 4/9 vs.3/28,P ＜ 0.05 ).Time to scar formation differed significantly between the patients with disseminated herpes and those with unilateral herpes zoster ( [7.44 ± 1.926]d vs.[3.89 ± 0.598]d,P＜0.01 ).Conclusions The immune function is weaker in malignant tumor patients complicated with disseminated herpes zoster than in those with local herpes zoster.Time to scar formation is also longer in the patients with disseminated herpes zoster. Key words: Malignant tumors; Disseminated Herpes zoster; Treatment