Abstract
The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. We performed a retrospective analysis of municipal databases of mother-to-child syphilis transmission. Pregnant women with syphilis were included. Group specific pregnancy outcomes were analyzed according to treatment. A total of 28 pregnant women were diagnosed with syphilis in 2012; 321 were diagnosed with syphilis in 2018. A prevalence of 0.14% was observed amongst pregnant women in Suzhou city from 2012–2018. Primary treatments included benzathine penicillin, ceftriaxone sodium or erythromycin when patients were allergic to Benzathine penicillin. The treatment coverage was 81.57%, and only 52.86% of pregnant women were adequately treated. Adverse pregnant outcomes were higher amongst untreated women. Expanding early screening coverage and promoting treatment were key to improving pregnancy outcomes amongst women with syphilis.
Highlights
The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes
Most maternal syphilis infections are latent, and untreated infections can lead to adverse pregnancy outcomes[1,2]
According to the National Statutory Infectious diseases reports, the prevalence of adult syphilis and maternal syphilis infections have increased in China since 2011
Summary
The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. There were an estimated 988,000 pregnant women infected with syphilis of which 52% experienced adverse pregnancy outcomes in 2016, including spontaneous abortions, stillbirths, preterm or low weight births, and clinical disease in infants[3,4]. Launched the global initiative for the elimination of MTCT of syphilis and developed global guidance to reduce congenital syphilis incidence to ≤50 or fewer per 100,000 live births[3] This included population-level antenatal care coverage for women ≥95%; coverage of syphilis testing of pregnant women ≥95%; and treatment coverage of syphilis-seropositive pregnant women ≥95%8. This study was the first to evaluate the prevalence of maternal syphilis, the effectiveness of treatment, and syphilis-associated pregnancy outcomes in Suzhou city
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
