Abstract
Adherence to treatment of diabetes mellitus (DM) can support successful therapy due to drug consumption over longtime periods. The objectives of this study are to evaluate the treatment adherence in DM as related to the quality of life and to evaluate factors associated with adherence and quality of life. This study used the Brief Medication Questionnaire (BMQ) to measure patients’ adherence. The Diabetes Quality of Life Clinical Trial Questionnaire (DQLCTQ) was used to measure patients’ quality of life. Subjects of this cross-sectional study were DM patients attending two private hospitals in Yogyakarta and who had been taking DM medications for more than 6 months. Statistical analyses used in this study were student’s t test and regression linear test. We recruited 65 DM patients who met the inclusion criteria. There were no significant differences of BMQ screens and DQLCTQ functions between monotherapy and combination therapy groups ( p> .05). The BMQ screens’ score of combination therapy were higher than monotherapy groups. The physical function, health distress, and mental health of combination therapy groups were higher than monotherapy group. The male patients had significantly higher score of regimen domain of BMQ than female patients (0.35 and 0.17, respectively). The older age has the lower score of treatment effect of DQLCTQ ( p< .05). The belief, recall, and belief about adverse drug reaction of BMQ have positive correlation with physical function ( r = .542, .424, and .640, respectively). Our study concluded that the quality of care, sex, and age may predict patients’ adherence and quality of life. There were positive correlation between patients’ adherence and quality of life.
Highlights
The success of medical treatment is influenced by the quality of health services and patient adherence to their treatment plan (Hsu et al, 2014)
The objectives of this research are to evaluate the treatment adherence in diabetes mellitus (DM) as related to the quality of life and to evaluate factors associated with adherence and quality of life
According to the correlation between Brief Medication Questionnaire (BMQ) domain and quality of life domain, we find that beliefs, recall, and beliefs about adverse event screens of BMQ had positive correlation with physical function (r = .542, .424, .640, respectively; p< .05, data were not shown)
Summary
The success of medical treatment is influenced by the quality of health services and patient adherence to their treatment plan (Hsu et al, 2014). A number of studies have shown that patient adherence during chronic treatment such as diabetes mellitus (DM), asthma, cardiovascular diseases, high cholesterol, breast cancer, and glaucoma is commonly low. The prevalence of nonadherence in diabetic patients is high, due to the duration of treatment, and may lead to an increase in mortality, morbidity, and other adverse effects (Blackburn, Swidrovich, & Lemstra, 2013; Delamater, 2006). The other previous study showed that nonadherence in oral antidiabetic treatment was associated with the incidence of end-stage renal disease, and the effect was more significant in the polytherapy of oral antidiabetic treatment and under the metformin polytherapy, besides other risk factors (Chang, Chien, Lin, Chiou, & Chiu, 2015)
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