Treating patients with a new coronavirus infection in the clinic of Izmerov Research Institute of Occupational Health

Abstract

Introduction. To comply with the order of the Government of the Russian Federation and the Ministry of Education and Science, the clinic of Izmerov Research Institute of Occupational Health received the necessary conditions for the provision of medical care to patients with a new coronavirus infection. The study aims to identify possible criteria for the positive dynamics of pneumonia caused by the SARS-CoV-2 virus and to describe the general characteristics of patients hospitalized in the COVID center of Izmerov Research Institute of Occupational Health. Materials and methods. The article describes the clinical, laboratory, and instrumental data of 68 patients with pneumonia caused by the SARS-CoV-2 virus hospitalized to continue treatment. Statistical analysis included descriptive statistics. The significance level was less than 0.05. Results. The COVID-center received patients with complaints of shortness of breath on exertion, an unproductive cough, general weakness, myalgias, headaches, and an impaired sense of smell and taste. The condition of the patients was moderate. O2 saturation in ambient air was 93% and higher. Computed tomography of the chest revealed lesions of the lung tissue (numerous peripheral seals of the "frosted glass" type of various shapes and lengths with areas of consolidation), mainly corresponding to bilateral polysegmental viral pneumonia CT 1-2 degrees. The most frequent changes in laboratory parameters in patients were increased values of ESR (51.16% of cases), D-dimer (50% of cases), CRP (22.06% of cases), relative values of monocytes (58.14% of cases), as well as low hemoglobin concentrations (23% of cases). Conclusions. In patients with a new coronavirus infection hospitalized to continue treatment in the COVID center of Izmerov Research Institute of Occupational Health, lung tissue lesions were detected, mainly corresponding to the moderate-severe form of bilateral polysegmental viral pneumonia (CT of the 1-2 degree). The most frequent changes in laboratory parameters in patients with COVID-19 were increased ESR values, D-dimer, CRP, relative values of monocytes, and low hemoglobin concentrations. Monocytes, being one of the indicators of activation of the immune defense, are a laboratory criterion for the positive dynamics of the course of new coronavirus infection.