Treating Chronic Hepatitis B Liver Fibrosis with a Combination of Biejiaruangan Compound Tablet and Entecavir with the aid of Real-time Shear Wave Elastography

Abstract

The aim of the present study was to observe clinical effect of the combination of Biejiaruangan compound tablet and entecavir under the assistance of real-time shear wave elastography for treating chronic hepatitis B liver fibrosis. About 180 patients who had been treated for chronic hepatitis B liver fibrosis at the Second Hospital of Yinzhou were enrolled. The real-time shear wave elastography was applied. The patients were randomized into the research group and the control group, each containing 90 patients. The control group was treated with entecavir, while the research group was treated with a combination of Biejiaruangan compound tablet and entecavir. The therapeutic efficacy was compared between both groups. Patients’ liver stiffness was obviously decreased after treatment (p<0.05). The research group had better hepatic function index than the control group (p<0.05). Moreover, a greater decrease in the hepatic fibrosis index and abdominal ultrasonography was observed in both groups after treatment, compared to those before therapy. The therapeutic efficacy of the research group was significantly better as well (p<0.05). For treating chronic hepatitis B liver fibrosis, a combination of Biejiaruangan compound tablet and entecavir with the aid of real-time shear wave elastography could achieve good clinical efficacy as well as significantly improve the therapeutic efficiency.