Treat Clinical Depression Using Antidepressants

Abstract

SSRIs are chemically distinct from traditional antidepressants such as tricyclic, tetracyclic, and monoamine oxidase inhibitors, but they share the same mechanism of action in that they selectively and potently inhibit serotonin neuronal reuptake while having no or very little effect on norepinephrine, acetylcholine, and histamine neuronal reuptake. As a result, when compared to other tricyclic and tetracyclic antidepressants, these drugs have fewer sedative, anticholinergic, and cardiovascular effects. Fluroxamine, fluroxamine, sertraline, indalpine, paroxetine, alproclate, femorxetine, and choroxamine are examples of SSRI drugs.