Travel distance and time to dermatology clinical trial sites: a cross-sectional geospatial analysis

Abstract

Despite increasing calls for diversity in clinical trial recruitment, data are lacking regarding disparities in access to dermatologic clinical trials. The objective of this study was to characterize travel distance and time to reach a dermatology clinical trial site considering patient demographic and location characteristics. We determined travel distance and time from every census tract population center in the United States to the nearest dermatologic clinical trial site using ArcGIS and linked travel estimates to demographic characteristics in each census tract based on 2020 American Community Survey. Nationally, patients travel an average of 14.3 miles and 19.7min to reach a dermatologic clinical trial site. Significantly shorter travel distance and time were observed for urban and Northeast residence, White and Asian race and private insurance relative to rural and Southern residence, Native American and Black race and public insurance (p < 0.001). These findings reveal disparate access regarding geographic region, rurality, race and insurance type, which may encourage investigators to allocate funding for travel assistance for underrepresented and disadvantaged groups to promote access and diversity in dermatologic clinical trials.