Tratamiento endourológico de estenosis ureterales. Estudio experimental comparativo

Abstract

Objectivesto compare efficacy and efficiency of two different endourological therapies for ureteral stricture, and to evaluate pathological reactions of the ureters following both endourological techniques. Material and methodsTen pigs underwent experimental induction of ureteral stricture. Four weeks later, ureteral strictures were demonstrated by imaging techniques. Animals were divided in two groups, according to the received therapy:-Group I. (5 pigs), endoballoon rupture endoureterotomy.-Group II (5 pigs), Acucise® balloon endoureterotomy.Ureteral stents were placed for 3 weeks following endoureterotomy. Animals were followed up four weeks after ureteral stents retrieval. ResultsIn all cases, ureteral stricture was proved four weeks after model induction. In one case from each group, it was needed a second balloon dilatation to achieve complete endoureterotomy. Leading to ureteral restenosis, stent migration occurred in one animal from group I. Success was achieved in 80% of cases from group I, and 100% of cases from group II. ConclusionsOur results suggest that both endourological therapies are effective. Nevertheless, a higher efficiency was proved with Acucise® endoureterotomy. Our pathological evidences do not support Davis’s studies on ureteral healing following endoureterotomy.