Abstract
The treatment of tuberculosis is based on two bacteriological pillars: the combination of drugs to avoid the selection of resistant Mycobacterium tuberculosis and the need for prolonged treatment to eliminate all bacilli in their different growth phases. Resistant tuberculosis and multidrug-resistant tuberculosis in particular are a global public health problem that also affects our setting. Cases of resistant tuberculosis have mainly increased in the population with human immunodeficiency virus (HIV) infection, immigrants, and socially disadvantaged individuals, but cases have also risen among the native population. This aspect reinforces the need to conduct systemic sensitivity studies of isolations. Various factors, such as allergies and drug toxicity, presence of liver disease, kidney failure, HIV infection, and pregnancy must be taken into account in regard to the treatment to be used.
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