Abstract
ObjectiveTo evaluate therapeutic response, among Venezuelan patients, to photodynamic therapy for basal-cell carcinoma with a chlorine-based photo-sensitizer compound. MethodsPatients included in the study had been diagnosed with single or multiple basalcell carcinomas, based on histopathology for adults, without gender or lesion localization discrimination, and were injected intravenously with the photo-sensitizer, Photolon. After a 3-hour interval, the tumoral zone (or zones) was illuminated with a 662nm wave length diode laser. ResultsTreatment was performed on 43 lesions in 16 patients with favorable response in every case; all clinical evidence of tumor(s) disappeared, which was confirmed by histopathology. Patients presented no complications attributable to treatment and remained under observation with no signs of oncologic disease for 24 months. ConclusionsThe efficiency and utility of photodynamic therapy with Photolon was demonstrated in the treatment of Venezuelan patients with multiple basal cell carcinoma lesions.
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