Abstract
Tracking SLO systems equipped to perform retinally targeted stimulus delivery typically use near-IR wavelengths for retinal imaging and eye tracking and visible wavelengths for stimulation. The lateral offsets between wavelengths caused by transverse chromatic aberration (TCA) must be carefully corrected in order to deliver targeted stimuli to the correct location on the retina. However, both the magnitude and direction of the TCA offset is dependent on the position of the eye's pupil relative to the incoming beam, and thus can change dynamically within an experimental session without proper control of the pupil position. The goals of this study were twofold: 1) To assess sources of variability in TCA alignments as a function of pupil displacements in an SLO and 2) To demonstrate a novel method for real-time correction of chromatic offsets. To summarize, we found substantial between- and within-subject variability in TCA in the presence of monochromatic aberrations. When adaptive optics was used to fully correct for monochromatic aberrations, variability both within and between observers was minimized. In a second experiment, we demonstrate that pupil tracking can be used to update stimulus delivery in the SLO in real time to correct for variability in chromatic offsets with pupil displacements.
Highlights
In the last decade, scanning laser ophthalmoscopes [1], or SLOs, both with [2] and without [3] adaptive optics [4], have been used to simultaneously image the retina, track eye motion [5], and deliver targeted, stabilized stimuli to the retina [6,7]
In this study we demonstrated that pupil tracking can be used to predict dynamic changes in transverse chromatic aberration (TCA) that occur with small shifts in pupil position
By updating stimulus delivery in accordance with the subjects’ pupil position, we successfully compensated for changes in TCA that occurred with pupil offsets (Experiment 2)
Summary
In the last decade, scanning laser ophthalmoscopes [1], or SLOs, both with [2] and without [3] adaptive optics [4], have been used to simultaneously image the retina, track eye motion [5], and deliver targeted, stabilized stimuli to the retina [6,7]. These systems have several advantages for both clinical research and psychophysics. Chromatic aberration has two components, longitudinal chromatic aberration (LCA) and transverse chromatic aberration (TCA)
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