Abstract
The Mu-related transposon Tn 5090, also called Tn 402, was observed to be highly selective for targets clustered in or close to recombination sites of serine-type recombinases in plasmids R388 and RP1. Transposition to the par area of RP1 responded strongly to a deletion in the gene of resolvase ParA. A search in sequence databanks revealed further insertions of Tn 5090/Tn 402 close to different genes of resolvases. These results imply that the target selection of Tn 5090 depends on a property that is shared among several serine recombinases.
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