Abstract
THE transport of sodium ions across the epithelium of the small intestine of the rat seems to be an active process (for a review of the evidence see Durbin, Curran and Solomon1). This active transport of sodium ions may be responsible for the potential difference existing across the gut wall, the mucosal side of which is negative with respect to the serosal side. In the jejunum the amplitude of this potential reported in the literature ranges from about 8 mV (refs. 2, 3) to 12 mV (ref. 4); the potentials in the ileum are smaller3.
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