Transport in Pulsatile Axisymmetric Stented Arterial Models From Location-Dependent Variations in Permeability and Mechanical Properties

Abstract

Drug-eluting stents (DESs) perform their antiproliferative effects through the use of localized drug delivery. The delivery may be computationally modeled to determine efficacy of the DES-tissue system and utilizes coupled convective and diffusive transport. Since the movement of solutes through the wall is via the coupled effects of convective and diffusive transport, the relative influence of these factors provides insight into the governing forces of localized DES drug delivery [1].