Abstract
Canine osteosarcoma and melanoma cell cultures, fresh canine cells obtained directly from a mammary carcinoma and from a transmissible venereal tumour have been successfully transplanted subcutaneously into Nude mice. The histological appearance of the osteosarcoma in mice resembled that seen when these cell cultures are transplanted in immunosuppressed dogs but some differences were apparent in the melanoma. The histological appearance of the mammary carcinoma and the transmissible venereal tumour resembled that of the neoplasm in the donor dog.
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