Abstract
AbstractWe have previously shown that lymphocyte‐mediated immunity to common bladder tumor antigens can be demonstrated in vitro. In this study we used two carcinomas and two sarcomas of the urinary bladder of BALB/c mice to immunize syngeneic animals against tumor‐specific transplantation antigens (TSTA) in order to determine whether common and/or individually unique antigens could be detected by resistance of the mice to challenge with tumor cells. Strong transplantation resistance was induced against each individual tumor line by immunizing with the respective line. No evidence could be obtained for the presence of TSTA common to the two carcinomas or to the two sarcomas (or to all four tumors).
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