Abstract

Sri Lanka Veterinary Journal (SLVJ) is a biannual peer reviewed official publication of the Sri Lanka Veterinary Association (SLVA), which has been in publication since 1953. It covers original research papers, review articles and communications on a wide range of veterinary topics with special emphasis on the Sri Lankan veterinary profession.

Highlights

  • Clinical examination, diagnosis, and monitoring of therapeutic response of deeply located intravaginal lesions of canine patients are crucial in veterinary practice

  • The objective of this study was to investigate the significance of using two-dimensional transperineal ultrasonography to characterize and monitor therapeutic effect on intravaginal Transmissible venereal tumour (TVT) with vincristine sulphate chemotherapy in dogs

  • Trans-perineal ultrasonography was performed in 12 dogs who were suffering from TVT

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Summary

Introduction

Diagnosis, and monitoring of therapeutic response of deeply located intravaginal lesions of canine patients are crucial in veterinary practice. Transmissible venereal tumour (TVT) grows mainly on the genitals of dogs (Igor et al, 2012; Tella et al, 2004). The diameter of the masses could vary initially (5-7 cm) and progress gradually deeper into the mucosa as multilobular lesions with diameters exceeding 10-15 cm (Otter et al, 2015). Intravenous vincristine sulphate 0.025 mg/kg, administered once a week for 3-6 weeks is reported to be one of the most effective chemotherapy protocols (de Silva, 1992; Otter et al, 2015; Purohit, 2008). Tella et al, (2004) suggested that the side effects of vincristine sulphateare being tolerated by many dogs with the accurate dosage, short and well-spaced duration of the therapy

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