Abstract
AbstractPronuclear eggs and blastocysts obtained from GR mice were transferred to mammary tumor virus‐free recipients. GR hybrid offspring were obtained which developed mammary tumors and transmitted virus to foster‐nursed test mice. Eggs of GR mice contain information leading to production of mammary tumor virus and development of tumors at adult age.Eggs of virus‐free mice were transplanted into GR mothers and the developing offspring subsequently delivered by Cesarean section. Intra‐uterine transmission of mammary tumor virus could not be demonstrated.Mice belonging to two different strains were foster‐nursed on GR hybrid mothers. These infected mice transmitted virus by means of their milk but not via the egg.The results are discussed and compared with observations made on transmission of leukemia viruses.
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