Abstract

Many brain disorders are currently untreatable. It has been suggested that taking a ‘translational’ approach to neuroscientific research might change this. We discuss what ‘translational neuroscience’ is and argue for the need to expand the traditional translational model if we are to make further advances in treating brain disorders.

Highlights

  • The World Health Organisation pinpoints brain disorders as ‘one of the greatest threats to public health’ (World Health Organisation, 2006), with one in four people affected by neurological or mental health conditions at some point in their lives (World Health Organisation, 2001)

  • Translational neuroscience aims to resolve this by transforming knowledge gained from basic science into interventions and applications for treating human disease

  • To understand why past decades of research have failed to result in successful treatments, we must understand what translational neuroscience is and how to effectively achieve it

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Summary

BRAIN COMMUNICATIONS

We discuss what ‘translational neuroscience’ is and argue for the need to expand the traditional translational model if we are to make further advances in treating brain disorders.

Introduction
Wet lab
Dry lab
Research culture
Public engagement
Science policy
Findings
In summary
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