Abstract
Translational bioinformatics is a rapidly emerging field of biomedical data sciences and informatics technologies that efficiently translate basic molecular, genetic, cellular, and clinical data into clinical products or health implications. Translational bioinformatics is now even more powerful than ever. The revolutionary progress in both bioinformatics and high-throughput genomics based on the flood of nucleotide sequences and microarray data will eventually transform the current practice of medicine forever, including diagnostics, therapeutics, and prognostics. Translational research is a paradigm for an alternative research approach to the dichotomy of basic and applied research. Its cross-disciplinary nature is a serious challenge caused by the compartmentalization of the current research training paradigm. Moreover, bioinformatics itself is interdisciplinary. To understand and correctly address the clinical needs for ultimately improving human health requires strategically-minded scientists, multi-skilled teams, and knowledge-driven data infrastructure for integrative analytics. Despite the barriers, linking the molecular world to the clinical world and vice versa will enormously benefit human health. Since its inception, the Translational Bioinformatics Conference (TBC) aims to highlight the multi-disciplinary nature of the research field and provides an opportunity to bring together and exchange ideas between international translational bioinformatics researchers. The Second Annual TBC 2012 in Jeju Island of South Korea provided the opportunity to substantially improve the understanding of complex and rare diseases and proposed new ways of approaching basic health problems by integrating genomic and clinical data.
Highlights
Open AccessTranslational bioinformatics has come of age: TBC 2012 collection Ju Han KimFrom Second Annual Translational Bioinformatics Conference (TBC 2012) Jeju Island, Korea. 13-16 October 2012
The revolutionary progress in both bioinformatics and high-throughput genomics based on the flood of nucleotide sequences and microarray data will eventually transform the current practice of medicine forever, including diagnostics, therapeutics, and prognostics
Personalized genomic and physiologic signatures Translational bioinformatics together with the ‘-omics’ investigates the contribution of genes, transcripts, proteins, and metabolic pathways to human physiology and the variations of its sub-systems that can lead to disease susceptibility
Summary
Open AccessTranslational bioinformatics has come of age: TBC 2012 collection Ju Han KimFrom Second Annual Translational Bioinformatics Conference (TBC 2012) Jeju Island, Korea. 13-16 October 2012. From Second Annual Translational Bioinformatics Conference (TBC 2012) Jeju Island, Korea. The revolutionary progress in both bioinformatics and high-throughput genomics based on the flood of nucleotide sequences and microarray data will eventually transform the current practice of medicine forever, including diagnostics, therapeutics, and prognostics.
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