Abstract

PurposeThe Sino-Nasal Outcome Test-22 (SNOT-22) is the most commonly used disease-specific quality of life questionnaire in rhinology. The purpose of this prospective study was to translate and validate SNOT-22 into Finnish.MethodsThe validation process followed the guidelines proposed for cross-cultural adaptation of health-related measures of quality of life. The study consisted of three groups: rhinologic out-patients (N = 96), FESS patients (N = 49) and healthy controls (N = 79). Out-patient and FESS groups completed the questionnaire twice (answers A and B), out-patients after two weeks and FESS patients after 3 months. Validity, reliability and responsiveness were evaluated.ResultsThe mean SNOT-22 sum score of the out-patient questionnaires were 35.3 points (answer A) and 32.4 points (answer B). ICC in out-patient group was 0.879. For the FESS patients, the mean pre- and postoperative (answer A and B) SNOT-22 sum scores were 46.8 and 21.9 points, respectively (p < 0.0001). The mean SNOT-22 of healthy controls was 8.9 points. The out-patients (answer A) and healthy controls had statistically significant difference in SNOT-22 scores (p < 0.0001).ConclusionsThe results of our study show that the validated Finnish version of the SNOT-22 questionnaire demonstrates good validity, reliability and responsiveness.

Highlights

  • Chronic rhinosinusitis (CRS) is a common medical problem affecting approximately 5–15% of people in Europe and United States [1,2,3]

  • Sino-Nasal Outcome Test-22 (SNOT-22) is composed of CRS-related items, which evaluate the severity of complaints that the patient has been experiencing over the past two weeks

  • Validation and translation process were performed according to the guidelines proposed for crosscultural adaptation of health-related measures of quality of life [14, 15]

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Summary

Introduction

Chronic rhinosinusitis (CRS) is a common medical problem affecting approximately 5–15% of people in Europe and United States [1,2,3]. Treatment of CRS is primarily conservative and surgery is warranted for patients refractory to medical therapy. Treatment effectiveness is evaluated utilizing sinonasal imaging and nasal endoscopy as well as different patient-reported. European Archives of Oto-Rhino-Laryngology (2021) 278:405–410 outcome measures (PROMs) most commonly assessing the disease-specific health-related QoL (HRQoL). The use of HRQoL questionnaires is rapidly growing in studies of clinical effectiveness and quality of care, and in clinical practise. A valid measure of rhinosinusitis patients’ health status and quality of life is required for the complete assessment of treatment effectiveness as well as a comparison of results of different studies

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