Abstract
BackgroundThe National Institute for Health Research (NIHR) has funded nine Collaborations for Leadership in Applied Health Research and Care (CLAHRCs). Each CLAHRC is a partnership between higher education institutions (HEIs) and the NHS in nine UK regional health economies. The CLAHRC for Leeds, York, and Bradford comprises two 'research themes' and three 'implementation themes.' One of these implementation themes is Translating Research into Practice in Leeds and Bradford (TRiPLaB). TRiPLaB aims to develop, implement, and evaluate methods for inducing and sustaining the uptake of research knowledge into practice in order to improve the quality of health services for the people of Leeds and Bradford.MethodsTRiPLaB is built around a three-stage, sequential, approach using separate, longitudinal case studies conducted with collaborating NHS organisations, TRiPLaB will select robust innovations to implement, conduct a theory-informed exploration of the local context using a variety of data collection and analytic methods, and synthesise the information collected to identify the key factors influencing the uptake and adoption of targeted innovations. This synthesis will inform the development of tailored, multifaceted, interventions designed to increase the translation of research findings into practice. Mixed research methods, including time series analysis, quasi-experimental comparison, and qualitative process evaluation, will be used to evaluate the impact of the implementation strategies deployed.ConclusionTRiPLaB is a theory-informed, systematic, mixed methods approach to developing and evaluating tailored implementation strategies aimed at increasing the translation of research-based findings into practice in one UK health economy. Through active collaboration with its local NHS, TRiPLaB aims to improve the quality of health services for the people of Leeds and Bradford and to contribute to research knowledge regarding the interaction between context and adoption behaviour in health services.
Highlights
The National Institute for Health Research (NIHR) has funded nine Collaborations for Leadership in Applied Health Research and Care (CLAHRCs)
Comparison of pre- and post-intervention scores The interrupted time series analysis will estimate the impact of the intervention upon process of care and health outcome measures; a comparison of preand post-intervention scores is necessary to estimate whether the intervention successfully changed the factors in the underlying theoretical framework that it was designed to target
TRiPLaB is a theory-informed, systematic, mixed methods approach to developing and evaluating tailored implementation strategies aimed at increasing the translation of research findings into clinical and service practice
Summary
Ethical approval for this study was given by York Research Ethics Committee (REC 10/H1311/1). Comparison of pre- and post-intervention scores The interrupted time series analysis will estimate the impact of the intervention upon process of care and health outcome measures; a comparison of preand post-intervention scores is necessary to estimate whether the intervention successfully changed the factors (for example, individual attitudes, social networks and team culture) in the underlying theoretical framework that it was designed to target (based on the data synthesis through multilevel modelling in TRiPLaB's development phase in each site) This 'meditational analysis' [9] is critical when evaluating the theory used to develop change interventions, as it will inform our understanding of why an intervention either works or fails to work in the ways we intended. The data will be analysed using a framework approach [21]: familiarisation with the data, identification of a thematic framework, indexing, charting, and mapping and interpretation with reference to the overall aim of TRiPLaB as well as the themes revealed by the data
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