Abstract
The present report describes a 50-year-old female recently diagnosed with multiple myeloma who presented with hepatosplenomegaly, miliary-type hyper enhancing liver tumors, and esophageal varices. We performed a transjugular liver biopsy when liver biopsy was requested to evaluate the miliary-type liver lesions. This was done to lower the risk of bleeding given the patient's anemia and probable portal hypertension. This approach was successful in safely providing diagnostic samples for surgical pathology and flow cytometry to assess the nature of focal miliary liver lesions. It also proved portal hypertension.
Highlights
Liver biopsy is a valuable diagnostic tool in the evaluation and management of patients with focal and non-focal liver disease
Gonzalez-Aguirre et al The present report describes a 50-year-old female recently diagnosed with multiple myeloma who presented with hepatosplenomegaly, miliary-type hyper enhancing liver tumors, and esophageal varices
The purpose of this review is to present an unusual presentation of multiple myeloma and show that a non-target transjugular liver biopsy can offer a safe approach with decrease bleeding risk in this patient with multiple focal lesions
Summary
Liver biopsy is a valuable diagnostic tool in the evaluation and management of patients with focal and non-focal liver disease. Liver biopsy has three major roles: 1) for diagnosis, 2) for assessment of prognosis (disease staging), and 3) to assist in making therapeutic decisions [1]. The present report describes a 50-year-old female recently diagnosed with multiple myeloma who presented with hepatosplenomegaly, miliary-type hyper enhancing liver tumors, and esophageal varices. In a patient with focal liver lesions usually the first approach to obtain tissue diagnosis is a target biopsy, either percutaneously or EUS guided [2]. The purpose of this review is to present an unusual presentation of multiple myeloma and show that a non-target transjugular liver biopsy can offer a safe approach with decrease bleeding risk in this patient with multiple focal lesions
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