Transition metal catalysis in fluorous media: extension of a new immobilization principle to biphasic and monophasic rhodium-catalyzed hydrosilylations of ketones and enones

Abstract

The title protocol utilizes CF 3C 6F 11 solutions of ClRh[P(CH 2CH 2(CF 2) n-1 CF 3) 3](in3) ( n=6, 8; 0.8-0.2 mol%) and toluene (biphasic conditions, 60°C) or hexanes or ether (monophasic conditions, 28–60°C) solutions of PhMe 2SiH and cyclic enones or ketones. Samples are cooled to room temperature or −30°C, and simple organic/fluorous phase separations remove products from the catalyst, which can be directly reused without loss of activity.