Abstract

AbstractA highly efficient regioselective synthesis of 3,4,5‐trisubstituted pyrazoles via transition metal‐ and oxidant‐free, three component [3+2] cycloaddition with thiazolidinedione chalcones, benzaldehydes and N‐tosylhydrazine is described. The reaction proceeds through C−C and C−N bond formations under mild reaction conditions to produce structurally diverse polysubstituted pyrazoles in moderate to good yields.

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