Transient VEP and psychophysical chromatic contrast thresholds in children and adults

Abstract

It has been found that humans are able to distinguish colours without luminance cues by about 2–4 months of age and that sensitivity to colour difference develops during childhood, reaching a peak around adolescence. This prolonged period of maturation is reflected by improvements in psychophysical threshold measures and by the VEP characteristics of morphology, latency and amplitude. An intra-individual comparison of VEP and psychophysical responses to isoluminant colour stimuli has not been made in children, however, and this was the aim of the present study. VEPs were recorded from 49 subjects, children (age range: 4.8–12.6 years) and adults (age range: 25.7–33.2 years). Psychophysical and VEP thresholds were both measured in 40 of those subjects. Nominally isoluminant chromatic (L–M) sinewave gratings were presented in onset-offset mode and identical stimuli were used for psychophysical and VEP recordings to allow comparison. In agreement with previous reports, morphology of the transient VEP in response to this stimulus differed considerably between children and adults. There was a significant difference between psychophysical and VEP thresholds in children, but not in adults. Our findings support and expand on previous work on maturation of the L–M chromatic pathway and indicate a larger discrepancy between VEP and psychophysical chromatic thresholds in children than in adults.