Transient Immunoglobulin and Antibody Production

Abstract

• Two patients with common varied immunodeficiency both had increased immunoglobulin responses for a limited period of time on acquiring a bacterial infection. In one patient a relatively short-lived high-antibody response was produced on vaccination with tetanus toxoid. Although the patients varied in their course of immunoglobulin and/or antibody production, our results demonstrate that some patients with common varied immunodeficiency are able to produce both under certain circumstances. (<i>Arch Intern Med</i>1983;143:1937-1940)