Abstract
A 33-year-old woman presented with five days of dysarthria and dysphagia. Her past medical history included Graves’ disease treated with a partial thyroidectomy five years earlier. On examination, she had tongue mounding and deviation to the right (Figs. 1 and and2).2). Other neurological and otorhinolaryngological findings were normal. Titers of herpes simplex virus and varicella-zoster virus antibodies were positive, but did not differ between the acute and convalescent phase sera. Brain magnetic resonance imaging (MRI) and magnetic resonance angiogram (MRA) findings were normal, and laboratory tests showed no evidence of inflammation. Idiopathic isolated unilateral hypoglossal nerve palsy was diagnosed. Figure 1. Right tongue mounding at rest. Figure 2. Tongue deviation to the right. While cranial nerves III, IV, VI and VII are more prone to idiopathic palsy, idiopathic unilateral hypoglossal nerve palsy is rare. With the limited number of cases reported, the male-to-female ratio appears even, the age of onset is widely distributed (20–69 years) and the majority of cases self-resolve.1 In acute isolated hypoglossal nerve palsy, malignancy, vascular pathology, herpes infection, systemic lupus erythematosus, multiple sclerosis and diabetic mononeuropathy have been reported as causes.1–3 Although the paired sera failed to show acute herpes infection in this case, reactivation of the disease could still be possible. Eight weeks after symptom onset, this patient fully recovered without intervention.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.