Abstract

Rapid advances in neonatal care have led to a dramatic surge in survival of the veryand extremely-premature infants. This is, however ,tempered by a concomitant increase in the incidence of severe neuromorbidity in the survivors, including cognitive delay, cerebral palsy, hearing loss, blindness, mental retardation, and epilepsy. Thus, an emerging challenge in newborn care is to translate the gains in survival achieved into gains in healthy survival, without the current high frequency of neurodevelopmental impairments.

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