Transient entrainment: the evolution of a medical concept from description to prescription.

Abstract

Entrainment is a phenomenon that has come to have considerable utility in cardiac electro-physiology diagnosis and treatment; specifically, to identify a zone of slow conduction in a reentrant circuit, a zone hypothetically vulnerable to intervention from the application of RF energy. The observation of entrainment has gone through an evolutionary sequence in the literature, from the initial simple observations of the phenomenon to the present stage of relatively fixed criteria of identification. This article follows the evolution of the specific features of the criteria of entrainment to their current crystallization into features that are suggested to prescribe sites for attempted ablation. This examination of the evolutionary course of the development of the conception of entrainment is of interest not only to cardiac electrophysiology, but also to philosophers of science, by illustrating how scientists emphasize and develop certain observations with the ultimate aim of applying the observations for successful intervention in pathological entities.