Abstract

The previous model of electrofocusing in a tapered capillary was extended to cover both focusing and non-focusing modes of capillary electrophoresis. The more general equation derived can be used either for tapered or for funnel-like segments of capillary for which the product of the local cross-section and the length-based separation coordinate is constant. The particular forms of the equation are used to discuss the changes in the vaRiance of a moving Gaussian zone in practically interesting cases of electrophoresis in a capillary of non-uniform cross-section.

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