Transient elastography in diagnosis of non-alcoholic fatty liver disease

Abstract

Clinical data of 113 patients with non-alcoholic fat liver disease (NAFLD) diagnosed by liver biopsy from January 2015 to January 2017 in Taizhou People′s Hospital were retrospectively reviewed. Patients all underwent transient elastographic (TE) examination and the values of fat attenuation index (FAI) were obtained. The hepatocyt fatty changes in pathological examination were scored as 0 ( 66%, n=18). There were significant differences in AST, Glu, TC and FAI among patients with hepatocyte fatty change scores 0, 1, 2 and 3, and the FAI was significantly correlated with the degree of fatty liver disease. The areas under the ROC curve (AUCs) of FAI in patients with hepatocyte fatty change scores 1, 2 and 3 were 0.78, 0.90 and 0.96, respectively. Logistic regression analysis showed that FAI was correlated with TG, TC and BMI. The results suggest that FAI in TE can be a non-invasive, rapid and objective evaluation method for patients with NAFLD. Key words: Fatty liver, non-alcoholic; Ultrasonograph; Elasticity imaging techniques