Abstract
Results: The total number of transfusions given in these two tertiary-care centers during 3-year study period was 68,290 with 3% of overall incidence of transfusion reactions, which is insignificant with the incidence of febrile reactions being highest (1.63%) and that of TRALI being lowest (0.0029%). Conclusion: Blood banks did not have facility for demonstrating human leukocyte antigen class antibody or leukoagglutinins in the blood donors. However, majority of blood donors were males repeat voluntary donors and previously not implicated in any blood transfusion reaction. The pre-transfusion cross-matching procedures were compatible. The possibility of trauma or injury may be the pathogenic trigger for TRALI.
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